Monday, October 22, 2007

migraine and PFO research


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A study written up in the October 2007 issue of Headache: The Journal of Head and Face Pain attempts to shed light on the possible correlation between patent foramen ovule (PFO) and migraine with aura.

According to the Cleveland Clinic, PFO is a hole in the heart caused by a failure of the left and right sides of the upper chambers of the heart to join after birth. The opening allows blood to circumvent the lungs, the body's filtering system for blood. This congenital defect is present in many people before birth, but seals itself naturally in 80% of people. PFO is fairly common, but rarely life threatening.

Relationship Between Migraine and PFO: A Study of 121 Patients

The study supports the idea that patients who experience migraine with aura are more likely than migraineurs without aura and non-migraineurs to have PFO. Fifty-four percent of patients with aura had PFO, while only 25 percent of migraineurs without aura and 25 percent of non-migraineurs had PFO. This difference is considered statistically significant.

Their research found no correlation between existence of PFO and type of aura, frequency of attack, sex, age or familial occurrence.

Sources:
- Patent Formen Ovule (PFO)

Related Posts:
- The Scoop on PFO

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