Mixing Large Doses of Common Painkiller and Caffeine May Increase Risk of Liver Damage
"People should be informed about this potentially harmful interaction," Nelson says. "The bottom line is that you don't have to stop taking acetaminophen or stop taking caffeine products, but you do need to monitor your intake more carefully when taking them together, especially if you drink alcohol."
Nelson points out that the bacteria used in the study were exposed to 'megadoses' of both acetaminophen and caffeine, much higher than most individuals would normally consume on a daily basis. Most people would similarly need to consume unusually high levels of these compounds together to have a dangerous effect, but the toxic threshold has not yet been determined, he says.
While the danger to humans is not clear at this point, if you regularly consume this combination or have concerns about whether your medications are exposing you to this danger, please discuss this research with your doctor.
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