Anticonvulsants in Migraine Prophylaxis
Diamox (acetazolamide), Klonopin (clonazepam), Lamictal (lamotrigine) and Sabril (vigabatrin) were no more effective than placebo in preventing migraine attacks. (Note: Vigabatrin has not been FDA approved for any purpose.) The study's authors said Neurontin (gabapentin) needs further study. They also suggested there is a great need for trials to compare the effectiveness of different anticonvulsants when used for migraine prevention.
Medline Plus Drug Information: Acetazolamide Oral
Epilepsy.com: Introduction to Sabril
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Content by Diana E. Lee.