Monday, May 19, 2008

migraine prevention news: Depakote, Topamax better than placebo


New to Somebody Heal Me? Subscribe to the Somebody Heal Me feed:
Subscribe in a reader or subscribe by e-mail. Follow me on Twitter @somebodyhealme.

A review of controlled studies published in the June 2008 edition of the journal Cephalalagia supports the notion that anticonvulsants Depakote and Topamax are much more effective than placebo in preventing migraine attacks. The study also indicates that other anticonvulsants sometimes used for migraine prevention are no more effective than placebo.

Anticonvulsants in Migraine Prophylaxis

Diamox (acetazolamide), Klonopin (clonazepam), Lamictal (lamotrigine) and Sabril (vigabatrin) were no more effective than placebo in preventing migraine attacks. (Note: Vigabatrin has not been FDA approved for any purpose.) The study's authors said Neurontin (gabapentin) needs further study. They also suggested there is a great need for trials to compare the effectiveness of different anticonvulsants when used for migraine prevention.

Sources:
Medline Plus Drug Information: Acetazolamide Oral
Epilepsy.com: Introduction to Sabril

Technorati Tags: , , , , , , , , , ,


Subscribe to the Somebody Heal Me feed: Subscribe in a reader or subscribe by e-mail.

Photo Sharing and Video Hosting at Photobucket Content by Diana E. Lee.