In 2006 the FDA issued a warning to patients using triptans and SSRIs or SNRIs (two classes of antidepressants) about a potentially life threatening interaction between the two known as serotonin syndrome. Yet, according to the headache specialist who wrote this article, neither he nor any of his colleagues with whom he has discussed the issue have ever seen a patient with the condition. He also questions whether the patients in the cases studied by the FDA were even experiencing serotonin syndrome.
Given that migraineurs are more likely than non-migraineurs to experience depression, discouraging the use of one important method of controlling depression (medication) is a serious issue. Furthermore, antidepressants can be a help to many people with frequent migraines in preventing their attacks.
Is an FDA Alert Harming Patients?
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Content by Diana E. Lee.