AAN: Epilepsy Drug Not Effective for Chronic Headaches
When headache patients don't respond to the more common preventative medications, they are often prescribed other medications in the same category. As an antiseizure medication, Keppra is in the same category of medications as Depakote and Topamax. Unfortunately, unlike those choices it does not seem to have the same effect on chronic headaches.
Researchers said Keppra achieved 3.9% better results than placebo, but that this was not statistically significant.
However, the researchers also said Keppra worked very well for some patients and remains a therapeutic option for those people. Therefore, it might make sense to try it if you've been on a lot of other options and haven't had any reduction in chronic headaches (and your doctor thinks you should try it).
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Content by Diana E. Lee.