Wednesday, September 09, 2009

Migraine Treatment Tonabersat No More Effective Than Placebo


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The journal Cephalalgia recently published an article about two randomized, double-blind, placebo controlled studies on the efficacy of the migraine treatment medication Tonabersat that found it to be no more effective than placebo in treating migraine attacks.

Tonabersat inhibits cortical spreading depression in the brain, which is thought by some to be the cause of migraine with aura. Other studies are trying to determine whether the drug is effective in preventing migraine attacks. Tonabersat has not been FDA approved for migraine treatment, prevention or any other purpose.

Sources:
Tonabersat, a Gap-Junction Modulator: Efficacy & Safety in Two Randomized, Placebo-Controlled, Dose Ranging Studies of Acute Migraine
Effects of Tonabersat on Migraine with Aura
Tonabersat Suppresses Aura but not Migraine Pain

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DISCLAIMER: Nothing on this site constitutes medical or legal advice. I am a patient who is engaged and educated and enjoys sharing my experiences and news about migraines, pain and depression. Please consult your own health care providers for advice on your unique situation.