The researcher whose work established this connection believes both hypermobility and migraine share roots of being related to collagen. Collagen is a protein that connects joints and tissues. His hypothesis is that if collagen is too elastic it leads to overly flexible joints and stretchy blood vessels. However, the notion that migraine originates in the blood vessels has gone out of fashion in recent years with the awareness that it's actually a neurological condition. Perhaps extremely elastic collagen makes the blood vessels more susceptible to the expansion and contraction observed in migraines.
This was an extremely small study and participants were taken from a connective tissue clinic, which may have skewed the results toward sicker people. It will certainly require larger studies to determine whether there is anything to this connection.
Extreme Flexibility Comes with Triple Migraine Risk
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Content by Diana E. Lee.DISCLAIMER: Nothing on this site constitutes medical or legal advice. I am a patient who is engaged and educated and enjoys sharing my experiences and news about migraines, pain and depression. Please consult your own health care providers for advice on your unique situation.