Wednesday, April 18, 2012

How to Access Midrin Equivalents for Migraine

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If you're a patient who has used Midrin as a migraine treatment medication, you may have been concerned that your pharmacy has been unable to fill your prescription. Headache disorders advocate Teri Robert has done some great reporting on this issue at and shared some good options for you to investigate so you have access to a medication with the same ingredients as Midrin. 

(1) Ask your doctor to write you a prescription you can take to a compounding pharmacy.
A compounding pharmacy prepares a prescription medication for an individual patient that isn't otherwise available for purchase. A compounded medication is prepared specifically for you. It doesn't exist until you take your prescription to the compounding pharmacy to have it filled. They can prepare pills for you with the same ingredients as Midrin. They are overseen by the state pharmacy board and the FDA, so you should feel just as safe using their services as you would any other pharmacy.

To find a compounding pharmacy in your area visit: Find a PCAB Pharmacy, do a Google search or check the local phone book.

(2) Ask your pharmacist about the Midrin-equivalent Isometh/Dich/Apap capsules produced by Macoven Pharmaceuticals based in Magnolia, Texas. 
While all other manufacturers of Midrin and its equivalents have stopped making their products, Macoven has assured Teri Robert, who has been closely following this issue, they intend to do what it takes to continue making their product available to patients.

(3) Try a similar medication called Prodrin.
While Midrin and its equivalents contain isometheptene mucate, acetaminophen and dichloralphenazone, Prodin contains isometheptene mucate, acetaminophen and caffeine. So while they are not identical, they are close enough to serve as an acceptable substitute for some patients.

I encourage those of you who use Midrin to keep up to date by following Teri's reporting on this issue at


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DISCLAIMER: Nothing on this site constitutes medical or legal advice. I am a patient who is engaged and educated and enjoys sharing my experiences and news about migraines, pain and depression. Please consult your own health care providers for advice on your unique situation.